Table 2 Factors associated with prescription nonadherence
From: Primary prescription adherence for obstructive lung disease in a primary care population
| Variable | Filled n (%) | Unfilled n (%) | OR (95% CI) |
|---|---|---|---|
| Age | |||
| 18–44 | 3718 (28.1) | 1261 (9.5) | 0.84 (0.72, 0.98) |
| 45–64 | 3871 (29.3) | 1171 (8.9) | 0.93 (0.80, 1.08) |
| 65–74 | 1319 (10.0) | 445 (3.4) | 0.83 (0.70, 0.98) |
| 75 + | 1130 (8.6) | 305 (2.3) | Ref |
| Income quintilea | |||
| NF | 281 (2.1) | 89 (0.7) | 1.14 (0.88, 1.47) |
| Q1 | 1749 (13.2) | 526 (4.0) | 1.20 (1.04, 1.37) |
| Q2 | 2093 (15.8) | 586 (4.4) | 1.30 (1.14, 1.48) |
| Q3 | 2068 (15.6) | 589 (4.5) | 1.28 (1.13, 1.46) |
| Q4 | 2077 (15.7) | 737 (5.6) | 1.04 (0.92, 1.17) |
| Q5 | 1770 (13.4) | 655 (5.0) | Ref |
| Charlson comorbidity indexb | |||
| 0 | 5873 (44.4) | 1762 (13.3) | Ref |
| 1–2 | 3663 (27.7) | 1232 (9.3) | 0.82 (0.75, 0.90) |
| 3 + | 502 (3.8) | 188 (1.4) | 0.66 (0.54, 0.80) |
| Depression diagnosis | |||
| No | 8922 (67.5) | 2795 (21.1) | Ref |
| Yes | 1116 (8.4) | 387 (2.9) | 0.87 (0.76, 0.98) |
| Number of hospitalizations in prior 1 year | |||
| 0 | 9030 (68.3) | 2882 (21.8) | Ref |
| 1–2 | 917 (6.9) | 273 (2.1) | 1.09 (0.93, 1.27) |
| 3 + | 91 (0.7) | 27 (0.2) | 1.08 (0.69, 1.70) |
| Number of ambulatory visits in prior 1 year | |||
| 0 | 876 (6.6) | 255 (1.9) | Ref |
| 1–2 | 2018 (15.3) | 660 (5.0) | 0.90 (0.76, 1.06) |
| 3–9 | 4925 (37.3) | 1568 (11.9) | 0.90 (0.76, 1.06) |
| 10 + | 2219 (16.8) | 699 (5.3) | 0.86 (0.71, 1.04) |
| Number of prescriptions at 4th level of ATC in prior 1 year | |||
| 0–2 | 3399 (25.7) | 1140 (8.6) | Ref |
| 3–5 | 2813 (21.3) | 910 (6.9) | 1.08 (0.96, 1.20) |
| 6 + | 3826 (29.0) | 1132 (8.6) | 1.22 (1.07, 1.38) |
| Number of ED visits in prior 1 year | |||
| 0 | 8752 (66.2) | 2787 (21.1) | Ref |
| 1–2 | 1028 (7.8) | 338 (2.6) | 0.95 (0.83, 1.08) |
| 3 + | 258 (2.0) | 57 (0.4) | 1.36 (1.01, 1.84) |
| Total | 10,038 | 3182 | |